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Title   암치료를 위한 RF 온열장치의 개발과 가온특성 ( Thermal Distribution and Development of RF Hyperthermia for Cancer Treatment )
Publicationinfo   1986 Jan; 018(02): 183-194.
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Abstract   The biological effects for the use of hyperthermia to treat malignant tumors has been well studied and encouraging clinical results have been reported. However, the engineering and technical aspects of hyperthermia for the deep-seated tumors has not been satisfactory. We have developed the RF capacitive hyperthermia device (Greenytherm-GY 8) by coopera- tion with Yonsei Cancer Center and Green Cross Medical Corporation. It was composed with 8-10 MHz RF generator, capacitive electrode, matching system, cooling system, tem- perature measuring thermocouples and control PC computer. We have measured the tempe- rature and thermal distribution in agar phantom, animals and human tumors. This RF hyperthermia device could be applied for clinical trials as result of following studies. 1) The generating power could be varied to 700-1500 W 2) The Radio-frequency for capacitive heating could be produced to 8-10 MHz 3) It was possible to contral the depth heating from skin by regulation the cooling tem- perature of bolus and choosing properly size electrodes. 4) Deep seated tumors (5-10 cm depth) might be heated to therapeutic temperature 40- 43' C. 5) Side effects and hot feeling on skin could be significantly reduced by cooling bolus and electric matching.
저 자   추성실(Sung Sil Chu),김귀언(Gwi Eon Kim),노준규(John J . K . Loh),김병수(Byung Soo Kim),박민용(Min Yong Park),양성화(Sung Wha Yang),정동균(Dong Kun Jung)